San Antonio Pets Alive! Second Chance Thrift Store is a nonprofit resale shop in West San Antonio dedicated to supporting local animal rescue efforts. Operated by San Antonio Pets Alive!, this community-focused thrift store helps fund lifesaving programs for dogs and cats throughout the city. Every purchase directly supports rescue, foster care, medical treatment, and adoption initiatives for pets in need.

What You’ll Find

Shoppers can browse a rotating inventory of gently used clothing, shoes, home décor, furniture, kitchenware, books, pet supplies, seasonal decorations, and unique vintage finds. Inventory changes frequently based on donations, so each visit offers a new treasure-hunting experience. Bargain hunters and thrift enthusiasts alike appreciate the affordable pricing and opportunity to shop with purpose.

Why Shop Here

• Supports local San Antonio animal rescue programs
• Affordable secondhand clothing and household goods
• Unique vintage and one-of-a-kind items
• Eco-friendly shopping that promotes reuse and sustainability
• Convenient West Side location on Marbach Road
• Newer store; just opened in February 2026

Community Impact

Unlike traditional thrift stores, the Second Chance Thrift Store operates with a mission beyond resale. Proceeds benefit lifesaving efforts that reduce euthanasia rates and provide medical care, fostering, and adoption opportunities for vulnerable pets. Donations and purchases both contribute to creating second chances—not just for items, but for animals in the San Antonio community.

Plan Your Visit

Located at 8336 Marbach Road, this San Antonio thrift store is open Tuesday through Saturday from 10 am to 6 pm. Whether you’re searching for affordable fashion, home essentials, or simply want to support a meaningful cause, San Antonio Pets Alive! Second Chance Thrift Store offers a rewarding way to shop local and give back.